Downstream Process Development

Mycenax develops efficient, scalable, and regulatory-compliant downstream processes for high-quality biologics. With expertise across mAbs, multi-specific antibodies, and recombinant proteins, we engineer purification strategies that deliver high purity, robust yields, and stable product quality, supporting cost-effective and scalable manufacturing solutions.

Proven Expertise

Over 100 successful downstream processes developed for protein therapeutics, ensuring both efficiency and scalability.

Accelerate Time to Market

Accelerated 4-week development platform for mAbs designed to deliver high-yield, cost-efficient purification processes.

AI-Driven Process Optimization

Cutting-edge AI-based mechanistic modeling and predictive simulation accelerate process development, enhance decision-making, and deliver higher purity, recovery, and process robustness.

Streamlined Purification Solutions

Accelerated purification strategy to rapidly deliver materials for early-stage studies

High-throughput purification platforms enabling efficient clone selection and quality evaluation

End-to-end downstream solutions designed for diverse protein types and needs

Integrated Process Development Capabilities

Achieve high recovery and product quality through data-driven process optimization

Shorten development timelines and lower COG by leveraging platform and standardized approaches

Ensure viral safety and regulatory compliance with robust process controls

Reduce impurities through advanced purification strategies

Proven Downstream Expertise

Mitigate aggregation and enhance process robustness

Robust enzymatic processing to support efficiency, purity, and batch-to-batch consistency

Solutions for high cell density harvest and clarification

High-throughput resin and condition screening for recombinant proteins

Service Highlight

Streamlined Purification Platform

Our streamlined 2-step purification platform delivers a faster, more efficient, and operationally reliable downstream process tailored specifically for monoclonal antibodies. By refining the traditional 3-step process, this focused, fit-for-purpose workflow demonstrates improved recovery while maintaining high product quality. The simplified design lowers production costs and shortens development timelines.  

• Streamlined 2-step purification enhances overall recovery without compromising purity.

High-Throughput Resin & Condition Screening

Rapid, data-driven resin and condition screening to identify effective purification strategies.

Membrane-Enabled Process Intensification

Integrating advanced membrane technologies to enhance purification efficiency, reduce cost and footprint, and support a more streamlined downstream workflow.